Gene-specific Break Apart Probe-OAZ3

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Catalog:	GBAFP-OAZ3-15206
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (OAZ3). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	OAZ3 Gene-specific Break Apart Probe is designed to detect potential OAZ3 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	Ornithine Decarboxylase Antizyme 3
Gene Summary [Provided by RefSeq]	The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 3, the third member of the antizyme family. Like antizymes 1 and 2, antizyme 3 inhibits ODC activity and polyamine uptake; however, it does not stimulate ODC degradation. Also, while antizymes 1 and 2 have broad tissue distribution, expression of antizyme 3 is restricted to haploid germ cells in testis, suggesting a distinct role for this antizyme in spermiogenesis. Antizyme 3 gene knockout studies showed that homozygous mutant male mice were infertile, and indicated the likely role of this antizyme in the formation of a rigid connection between the sperm head and tail during spermatogenesis. Alternatively spliced transcript variants encoding different isoforms, including one resulting from the use of non-AUG (CUG) translation initiation codon, have been found for this gene. [provided by RefSeq, Dec 2014]
Gene Symbol	OAZ3
Location	1q21.3
Chromosome	Chromosome1
Coordinates	This gene maps to 151735444-151743806 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	OR; GR	GBAFP-OAZ3-15206-ORGR	573nm;515nm	548nm;491nm
2	AQ; OR	GBAFP-OAZ3-15206-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-OAZ3-15206-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-OAZ3-15206-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-OAZ3-15206-GRGO	515nm;551nm	491nm;525nm
6	GR; OR	GBAFP-OAZ3-15206-GROR	515nm;573nm	491nm;548nm
7	GR; RE	GBAFP-OAZ3-15206-GRRE	515nm;599nm	491nm;580nm
8	RE; GO	GBAFP-OAZ3-15206-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-OAZ3-15206-REGR	599nm;515nm	580nm;491nm

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