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| Catalog: | GBAFP-MMP12-05133 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (MMP12). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | MMP12 Gene-specific Break Apart Probe is designed to detect potential MMP12 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Matrix Metallopeptidase 12 |
| Gene Summary [Provided by RefSeq] | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016] |
| Gene Symbol | MMP12 |
| Location | 11q22.2 |
| Chromosome | Chromosome11 |
| Coordinates | This gene maps to 102733463-102745764 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-MMP12-05133-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-MMP12-05133-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-MMP12-05133-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-MMP12-05133-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-MMP12-05133-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-MMP12-05133-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-MMP12-05133-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-MMP12-05133-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-MMP12-05133-REGR | 599nm;515nm | 580nm;491nm |
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