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| Catalog: | GBAFP-MKRN1-05156 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (MKRN1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | MKRN1 Gene-specific Break Apart Probe is designed to detect potential MKRN1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Makorin Ring Finger Protein 1 |
| Gene Summary [Provided by RefSeq] | This gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co-regulator, and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thought to regulate RNA polymerase II-catalyzed transcription. Substrates for this protein's E3 ubiquitin ligase activity include the capsid protein of the West Nile virus and the catalytic subunit of the telomerase ribonucleoprotein. This protein controls cell cycle arrest and apoptosis by regulating p21, a cell cycle regulator, and the tumor suppressor protein p53. Pseudogenes of this gene are present on chromosomes 1, 3, 9, 12 and 20, and on the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] |
| Gene Symbol | MKRN1 |
| Location | 7q34 |
| Chromosome | Chromosome7 |
| Coordinates | This gene maps to 140152839-140179369 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-MKRN1-05156-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-MKRN1-05156-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-MKRN1-05156-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-MKRN1-05156-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-MKRN1-05156-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-MKRN1-05156-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-MKRN1-05156-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-MKRN1-05156-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-MKRN1-05156-REGR | 599nm;515nm | 580nm;491nm |
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