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| Catalog: | GBAFP-MBD4-04424 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (MBD4). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | MBD4 Gene-specific Break Apart Probe is designed to detect potential MBD4 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Methyl-CpG Binding Domain 4, DNA Glycosylase |
| Gene Summary [Provided by RefSeq] | The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013] |
| Gene Symbol | MBD4 |
| Location | 3q21.3 |
| Chromosome | Chromosome3 |
| Coordinates | This gene maps to 129149792-129158852 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-MBD4-04424-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-MBD4-04424-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-MBD4-04424-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-MBD4-04424-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-MBD4-04424-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-MBD4-04424-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-MBD4-04424-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-MBD4-04424-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-MBD4-04424-REGR | 599nm;515nm | 580nm;491nm |
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