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| Catalog: | GBAFP-KNG1-13456 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (KNG1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | KNG1 Gene-specific Break Apart Probe is designed to detect potential KNG1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Kininogen 1 |
| Gene Summary [Provided by RefSeq] | This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014] |
| Gene Symbol | KNG1 |
| Location | 3q27.3 |
| Chromosome | Chromosome3 |
| Coordinates | This gene maps to 186435097-186462199 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-KNG1-13456-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-KNG1-13456-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-KNG1-13456-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-KNG1-13456-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-KNG1-13456-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-KNG1-13456-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-KNG1-13456-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-KNG1-13456-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-KNG1-13456-REGR | 599nm;515nm | 580nm;491nm |
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