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| Catalog: | GBAFP-KLHL12-03806 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (KLHL12). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | KLHL12 Gene-specific Break Apart Probe is designed to detect potential KLHL12 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Kelch Like Family Member 12 |
| Gene Summary [Provided by RefSeq] | This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| Gene Symbol | KLHL12 |
| Location | 1q32.1 |
| Chromosome | Chromosome1 |
| Coordinates | This gene maps to 202860229-202896371 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-KLHL12-03806-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-KLHL12-03806-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-KLHL12-03806-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-KLHL12-03806-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-KLHL12-03806-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-KLHL12-03806-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-KLHL12-03806-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-KLHL12-03806-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-KLHL12-03806-REGR | 599nm;515nm | 580nm;491nm |
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