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| Catalog: | GBAFP-KISS1-03823 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (KISS1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | KISS1 Gene-specific Break Apart Probe is designed to detect potential KISS1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | KiSS-1 Metastasis-suppressor |
| Gene Summary [Provided by RefSeq] | This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Mar 2012] |
| Gene Symbol | KISS1 |
| Location | 1q32.1 |
| Chromosome | Chromosome1 |
| Coordinates | This gene maps to 204159468-204165619 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-KISS1-03823-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-KISS1-03823-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-KISS1-03823-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-KISS1-03823-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-KISS1-03823-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-KISS1-03823-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-KISS1-03823-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-KISS1-03823-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-KISS1-03823-REGR | 599nm;515nm | 580nm;491nm |
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