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| Catalog: | GBAFP-ITGA4-13181 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (ITGA4). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | ITGA4 Gene-specific Break Apart Probe is designed to detect potential ITGA4 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Integrin Subunit Alpha 4 |
| Gene Summary [Provided by RefSeq] | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |
| Gene Symbol | ITGA4 |
| Location | 2q31.3 |
| Chromosome | Chromosome2 |
| Coordinates | This gene maps to 182321618-182402468 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-ITGA4-13181-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-ITGA4-13181-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-ITGA4-13181-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-ITGA4-13181-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-ITGA4-13181-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-ITGA4-13181-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-ITGA4-13181-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-ITGA4-13181-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-ITGA4-13181-REGR | 599nm;515nm | 580nm;491nm |
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