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| Catalog: | GBAFP-GZMB-03113 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (GZMB). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | GZMB Gene-specific Break Apart Probe is designed to detect potential GZMB rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Granzyme B |
| Gene Summary [Provided by RefSeq] | This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016] |
| Gene Symbol | GZMB |
| Location | 14q12 |
| Chromosome | Chromosome14 |
| Coordinates | This gene maps to 25100160-25103432 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-GZMB-03113-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-GZMB-03113-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-GZMB-03113-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-GZMB-03113-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-GZMB-03113-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-GZMB-03113-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-GZMB-03113-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-GZMB-03113-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-GZMB-03113-REGR | 599nm;515nm | 580nm;491nm |
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