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| Catalog: | GBAFP-GSTA2-03143 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (GSTA2). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | GSTA2 Gene-specific Break Apart Probe is designed to detect potential GSTA2 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Glutathione S-transferase Alpha 2 |
| Gene Summary [Provided by RefSeq] | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008] |
| Gene Symbol | GSTA2 |
| Location | 6p12.2 |
| Chromosome | Chromosome6 |
| Coordinates | This gene maps to 52614884-52628361 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-GSTA2-03143-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-GSTA2-03143-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-GSTA2-03143-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-GSTA2-03143-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-GSTA2-03143-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-GSTA2-03143-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-GSTA2-03143-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-GSTA2-03143-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-GSTA2-03143-REGR | 599nm;515nm | 580nm;491nm |
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