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Gene-specific Break Apart Probe-GSTA2

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Catalog: GBAFP-GSTA2-03143
Classification: Gene-specific Break Apart Probes
Description: Our Gene-specific Break Apart Probes usually target the flanks of the target gene (GSTA2). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application: GSTA2 Gene-specific Break Apart Probe is designed to detect potential GSTA2 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity: 20 Tests
Probe Kits Volume (µL): 40 μL
Hybridization Solution (µL): 200 μL
Turnaround Time: Within 10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Shipping Conditions: -20℃
Storage Conditions: Store at -20℃ and avoid light;

Gene Details

Gene Name Glutathione S-transferase Alpha 2
Gene Summary [Provided by RefSeq] Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008]
Gene Symbol GSTA2
Location 6p12.2
Chromosome Chromosome6
Coordinates This gene maps to 52614884-52628361 in GRCh37 coordinates.
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 GR; OR GBAFP-GSTA2-03143-GROR 515nm;573nm 491nm;548nm
2 AQ; OR GBAFP-GSTA2-03143-AQOR 467nm;573nm 418nm;548nm
3 GO; GR GBAFP-GSTA2-03143-GOGR 551nm;515nm 525nm;491nm
4 GO; RE GBAFP-GSTA2-03143-GORE 551nm;599nm 525nm;580nm
5 GR; GO GBAFP-GSTA2-03143-GRGO 515nm;551nm 491nm;525nm
6 GR; RE GBAFP-GSTA2-03143-GRRE 515nm;599nm 491nm;580nm
7 OR; GR GBAFP-GSTA2-03143-ORGR 573nm;515nm 548nm;491nm
8 RE; GO GBAFP-GSTA2-03143-REGO 599nm;551nm 580nm;525nm
9 RE; GR GBAFP-GSTA2-03143-REGR 599nm;515nm 580nm;491nm

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