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| Catalog: | GBAFP-GRM3-12562 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (GRM3). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | GRM3 Gene-specific Break Apart Probe is designed to detect potential GRM3 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Glutamate Metabotropic Receptor 3 |
| Gene Summary [Provided by RefSeq] | L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Jul 2008] |
| Gene Symbol | GRM3 |
| Location | 7q21.11-q21.12 |
| Chromosome | Chromosome7 |
| Coordinates | This gene maps to 86273229-86494192 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-GRM3-12562-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-GRM3-12562-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-GRM3-12562-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-GRM3-12562-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-GRM3-12562-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-GRM3-12562-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-GRM3-12562-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-GRM3-12562-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-GRM3-12562-REGR | 599nm;515nm | 580nm;491nm |
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