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| Catalog: | GBAFP-FZD6-12318 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (FZD6). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | FZD6 Gene-specific Break Apart Probe is designed to detect potential FZD6 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Frizzled Class Receptor 6 |
| Gene Summary [Provided by RefSeq] | This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011] |
| Gene Symbol | FZD6 |
| Location | 8q22.3 |
| Chromosome | Chromosome8 |
| Coordinates | This gene maps to 104310660-104345094 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-FZD6-12318-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-FZD6-12318-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-FZD6-12318-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-FZD6-12318-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-FZD6-12318-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-FZD6-12318-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-FZD6-12318-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-FZD6-12318-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-FZD6-12318-REGR | 599nm;515nm | 580nm;491nm |
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