Gene-specific Break Apart Probe-FKBP4

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Catalog:	GBAFP-FKBP4-12136
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (FKBP4). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	FKBP4 Gene-specific Break Apart Probe is designed to detect potential FKBP4 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	FK506 Binding Protein 4
Gene Summary [Provided by RefSeq]	The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene. [provided by RefSeq, Sep 2008]
Gene Symbol	FKBP4
Location	12p13.33
Chromosome	Chromosome12
Coordinates	This gene maps to 2904107-2914587 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	OR; GR	GBAFP-FKBP4-12136-ORGR	573nm;515nm	548nm;491nm
2	AQ; OR	GBAFP-FKBP4-12136-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-FKBP4-12136-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-FKBP4-12136-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-FKBP4-12136-GRGO	515nm;551nm	491nm;525nm
6	GR; OR	GBAFP-FKBP4-12136-GROR	515nm;573nm	491nm;548nm
7	GR; RE	GBAFP-FKBP4-12136-GRRE	515nm;599nm	491nm;580nm
8	RE; GO	GBAFP-FKBP4-12136-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-FKBP4-12136-REGR	599nm;515nm	580nm;491nm

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