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| Catalog: | GBAFP-FDPS-12179 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (FDPS). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | FDPS Gene-specific Break Apart Probe is designed to detect potential FDPS rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Farnesyl Diphosphate Synthase |
| Gene Summary [Provided by RefSeq] | This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008] |
| Gene Symbol | FDPS |
| Location | 1q22 |
| Chromosome | Chromosome1 |
| Coordinates | This gene maps to 155278538-155290457 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-FDPS-12179-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-FDPS-12179-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-FDPS-12179-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-FDPS-12179-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-FDPS-12179-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-FDPS-12179-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-FDPS-12179-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-FDPS-12179-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-FDPS-12179-REGR | 599nm;515nm | 580nm;491nm |
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