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| Catalog: | GBAFP-FBXW8-12077 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (FBXW8). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | FBXW8 Gene-specific Break Apart Probe is designed to detect potential FBXW8 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | F-box And WD Repeat Domain Containing 8 |
| Gene Summary [Provided by RefSeq] | This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Gene Symbol | FBXW8 |
| Location | 12q24.22 |
| Chromosome | Chromosome12 |
| Coordinates | This gene maps to 117348760-117468953 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-FBXW8-12077-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-FBXW8-12077-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-FBXW8-12077-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-FBXW8-12077-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-FBXW8-12077-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-FBXW8-12077-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-FBXW8-12077-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-FBXW8-12077-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-FBXW8-12077-REGR | 599nm;515nm | 580nm;491nm |
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