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| Catalog: | GBAFP-FADD-11976 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (FADD). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | FADD Gene-specific Break Apart Probe is designed to detect potential FADD rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Fas Associated Via Death Domain |
| Gene Summary [Provided by RefSeq] | The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008] |
| Gene Symbol | FADD |
| Location | 11q13.3 |
| Chromosome | Chromosome11 |
| Coordinates | This gene maps to 70049268-70053508 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-FADD-11976-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-FADD-11976-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-FADD-11976-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-FADD-11976-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-FADD-11976-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-FADD-11976-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-FADD-11976-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-FADD-11976-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-FADD-11976-REGR | 599nm;515nm | 580nm;491nm |
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