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| Catalog: | GBAFP-F9-11982 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (F9). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | F9 Gene-specific Break Apart Probe is designed to detect potential F9 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Coagulation Factor IX |
| Gene Summary [Provided by RefSeq] | This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015] |
| Gene Symbol | F9 |
| Location | Xq27.1 |
| Chromosome | ChromosomeX |
| Coordinates | This gene maps to 138612894-138645617 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-F9-11982-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-F9-11982-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-F9-11982-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-F9-11982-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-F9-11982-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-F9-11982-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-F9-11982-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-F9-11982-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-F9-11982-REGR | 599nm;515nm | 580nm;491nm |
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