Gene-specific Break Apart Probe-ESRRG

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Catalog:	GBAFP-ESRRG-02327
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (ESRRG). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	ESRRG Gene-specific Break Apart Probe is designed to detect potential ESRRG rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	Estrogen Related Receptor Gamma
Gene Summary [Provided by RefSeq]	This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region. [provided by RefSeq, Aug 2011]
Gene Symbol	ESRRG
Location	1q41
Chromosome	Chromosome1
Coordinates	This gene maps to 216676587-217311097 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	GR; OR	GBAFP-ESRRG-02327-GROR	515nm;573nm	491nm;548nm
2	AQ; OR	GBAFP-ESRRG-02327-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-ESRRG-02327-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-ESRRG-02327-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-ESRRG-02327-GRGO	515nm;551nm	491nm;525nm
6	GR; RE	GBAFP-ESRRG-02327-GRRE	515nm;599nm	491nm;580nm
7	OR; GR	GBAFP-ESRRG-02327-ORGR	573nm;515nm	548nm;491nm
8	RE; GO	GBAFP-ESRRG-02327-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-ESRRG-02327-REGR	599nm;515nm	580nm;491nm

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