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| Catalog: | GBAFP-DHFR-02014 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (DHFR). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | DHFR Gene-specific Break Apart Probe is designed to detect potential DHFR rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Dihydrofolate Reductase |
| Gene Summary [Provided by RefSeq] | Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014] |
| Gene Symbol | DHFR |
| Location | 5q14.1 |
| Chromosome | Chromosome5 |
| Coordinates | This gene maps to 79922044-79950800 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-DHFR-02014-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-DHFR-02014-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-DHFR-02014-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-DHFR-02014-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-DHFR-02014-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-DHFR-02014-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-DHFR-02014-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-DHFR-02014-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-DHFR-02014-REGR | 599nm;515nm | 580nm;491nm |
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