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| Catalog: | GBAFP-DEFA4-01888 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (DEFA4). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | DEFA4 Gene-specific Break Apart Probe is designed to detect potential DEFA4 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Defensin Alpha 4 |
| Gene Summary [Provided by RefSeq] | Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Oct 2014] |
| Gene Symbol | DEFA4 |
| Location | 8p23.1 |
| Chromosome | Chromosome8 |
| Coordinates | This gene maps to 6793344-6795786 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-DEFA4-01888-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-DEFA4-01888-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-DEFA4-01888-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-DEFA4-01888-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-DEFA4-01888-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-DEFA4-01888-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-DEFA4-01888-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-DEFA4-01888-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-DEFA4-01888-REGR | 599nm;515nm | 580nm;491nm |
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