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| Catalog: | GBAFP-CYP46A1-11323 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (CYP46A1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | CYP46A1 Gene-specific Break Apart Probe is designed to detect potential CYP46A1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Cytochrome P450 Family 46 Subfamily A Member 1 |
| Gene Summary [Provided by RefSeq] | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008] |
| Gene Symbol | CYP46A1 |
| Location | 14q32.2 |
| Chromosome | Chromosome14 |
| Coordinates | This gene maps to 100150754-100193638 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-CYP46A1-11323-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-CYP46A1-11323-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-CYP46A1-11323-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-CYP46A1-11323-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-CYP46A1-11323-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-CYP46A1-11323-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-CYP46A1-11323-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-CYP46A1-11323-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-CYP46A1-11323-REGR | 599nm;515nm | 580nm;491nm |
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