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| Catalog: | GBAFP-CYP1A2-11339 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (CYP1A2). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | CYP1A2 Gene-specific Break Apart Probe is designed to detect potential CYP1A2 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Cytochrome P450 Family 1 Subfamily A Member 2 |
| Gene Summary [Provided by RefSeq] | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008] |
| Gene Symbol | CYP1A2 |
| Location | 15q24.1 |
| Chromosome | Chromosome15 |
| Coordinates | This gene maps to 75041186-75048948 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-CYP1A2-11339-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-CYP1A2-11339-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-CYP1A2-11339-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-CYP1A2-11339-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-CYP1A2-11339-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-CYP1A2-11339-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-CYP1A2-11339-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-CYP1A2-11339-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-CYP1A2-11339-REGR | 599nm;515nm | 580nm;491nm |
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