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| Catalog: | GBAFP-CYP17A1-01748 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (CYP17A1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | CYP17A1 Gene-specific Break Apart Probe is designed to detect potential CYP17A1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Cytochrome P450 Family 17 Subfamily A Member 1 |
| Gene Summary [Provided by RefSeq] | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008] |
| Gene Symbol | CYP17A1 |
| Location | 10q24.32 |
| Chromosome | Chromosome10 |
| Coordinates | This gene maps to 104590287-104597290 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-CYP17A1-01748-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-CYP17A1-01748-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-CYP17A1-01748-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-CYP17A1-01748-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-CYP17A1-01748-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-CYP17A1-01748-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-CYP17A1-01748-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-CYP17A1-01748-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-CYP17A1-01748-REGR | 599nm;515nm | 580nm;491nm |
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