Gene-specific Break Apart Probe-CST3

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Catalog:	GBAFP-CST3-01692
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (CST3). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	CST3 Gene-specific Break Apart Probe is designed to detect potential CST3 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	Cystatin C
Gene Summary [Provided by RefSeq]	The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein. [provided by RefSeq, Nov 2014]
Gene Symbol	CST3
Location	20p11.21
Chromosome	Chromosome20
Coordinates	This gene maps to 23614293-23618574 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	GR; OR	GBAFP-CST3-01692-GROR	515nm;573nm	491nm;548nm
2	AQ; OR	GBAFP-CST3-01692-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-CST3-01692-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-CST3-01692-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-CST3-01692-GRGO	515nm;551nm	491nm;525nm
6	GR; RE	GBAFP-CST3-01692-GRRE	515nm;599nm	491nm;580nm
7	OR; GR	GBAFP-CST3-01692-ORGR	573nm;515nm	548nm;491nm
8	RE; GO	GBAFP-CST3-01692-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-CST3-01692-REGR	599nm;515nm	580nm;491nm

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