Gene-specific Break Apart Probe-CRYGS

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Catalog:	GBAFP-CRYGS-01599
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (CRYGS). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	CRYGS Gene-specific Break Apart Probe is designed to detect potential CRYGS rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	Crystallin Gamma S
Gene Summary [Provided by RefSeq]	Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. This gene encodes a protein initially considered to be a beta-crystallin but the encoded protein is monomeric and has greater sequence similarity to other gamma-crystallins. This gene encodes the most significant gamma-crystallin in adult eye lens tissue. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq, Jul 2008]
Gene Symbol	CRYGS
Location	3q27.3
Chromosome	Chromosome3
Coordinates	This gene maps to 186256231-186262167 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	GR; OR	GBAFP-CRYGS-01599-GROR	515nm;573nm	491nm;548nm
2	AQ; OR	GBAFP-CRYGS-01599-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-CRYGS-01599-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-CRYGS-01599-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-CRYGS-01599-GRGO	515nm;551nm	491nm;525nm
6	GR; RE	GBAFP-CRYGS-01599-GRRE	515nm;599nm	491nm;580nm
7	OR; GR	GBAFP-CRYGS-01599-ORGR	573nm;515nm	548nm;491nm
8	RE; GO	GBAFP-CRYGS-01599-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-CRYGS-01599-REGR	599nm;515nm	580nm;491nm

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