Gene-specific Break Apart Probe-CRYBA1

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Catalog:	GBAFP-CRYBA1-11202
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (CRYBA1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	CRYBA1 Gene-specific Break Apart Probe is designed to detect potential CRYBA1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	Crystallin Beta A1
Gene Summary [Provided by RefSeq]	Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'. [provided by RefSeq, Jul 2008]
Gene Symbol	CRYBA1
Location	17q11.2
Chromosome	Chromosome17
Coordinates	This gene maps to 27573874-27581502 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	OR; GR	GBAFP-CRYBA1-11202-ORGR	573nm;515nm	548nm;491nm
2	AQ; OR	GBAFP-CRYBA1-11202-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-CRYBA1-11202-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-CRYBA1-11202-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-CRYBA1-11202-GRGO	515nm;551nm	491nm;525nm
6	GR; OR	GBAFP-CRYBA1-11202-GROR	515nm;573nm	491nm;548nm
7	GR; RE	GBAFP-CRYBA1-11202-GRRE	515nm;599nm	491nm;580nm
8	RE; GO	GBAFP-CRYBA1-11202-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-CRYBA1-11202-REGR	599nm;515nm	580nm;491nm

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