CONTACT SUPPORT
Online Inquiry
| Catalog: | GBAFP-CRH-01606 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (CRH). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | CRH Gene-specific Break Apart Probe is designed to detect potential CRH rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Corticotropin Releasing Hormone |
| Gene Summary [Provided by RefSeq] | This gene encodes a member of the corticotropin-releasing factor family. The encoded preproprotein is proteolytically processed to generate the mature neuropeptide hormone. In response to stress, this hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus, binds to corticotropin releasing hormone receptors and stimulates the release of adrenocorticotropic hormone from the pituitary gland. Marked reduction in this protein has been observed in association with Alzheimer's disease. Autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes, and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Nov 2015] |
| Gene Symbol | CRH |
| Location | 8q13.1 |
| Chromosome | Chromosome8 |
| Coordinates | This gene maps to 67088611-67090846 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-CRH-01606-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-CRH-01606-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-CRH-01606-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-CRH-01606-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-CRH-01606-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-CRH-01606-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-CRH-01606-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-CRH-01606-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-CRH-01606-REGR | 599nm;515nm | 580nm;491nm |
Other Products