Gene-specific Break Apart Probe-CLEC4M

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Catalog:	GBAFP-CLEC4M-11110
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (CLEC4M). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	CLEC4M Gene-specific Break Apart Probe is designed to detect potential CLEC4M rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	C-type Lectin Domain Family 4 Member M
Gene Summary [Provided by RefSeq]	This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835; often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.[provided by RefSeq, Feb 2009]
Gene Symbol	CLEC4M
Location	19p13.2
Chromosome	Chromosome19
Coordinates	This gene maps to 7828034-7834491 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	OR; GR	GBAFP-CLEC4M-11110-ORGR	573nm;515nm	548nm;491nm
2	AQ; OR	GBAFP-CLEC4M-11110-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-CLEC4M-11110-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-CLEC4M-11110-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-CLEC4M-11110-GRGO	515nm;551nm	491nm;525nm
6	GR; OR	GBAFP-CLEC4M-11110-GROR	515nm;573nm	491nm;548nm
7	GR; RE	GBAFP-CLEC4M-11110-GRRE	515nm;599nm	491nm;580nm
8	RE; GO	GBAFP-CLEC4M-11110-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-CLEC4M-11110-REGR	599nm;515nm	580nm;491nm

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