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| Catalog: | GBAFP-CKMT1B-11012 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (CKMT1B). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | CKMT1B Gene-specific Break Apart Probe is designed to detect potential CKMT1B rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Creatine Kinase, Mitochondrial 1B |
| Gene Summary [Provided by RefSeq] | Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008] |
| Gene Symbol | CKMT1B |
| Location | 15q15.3 |
| Chromosome | Chromosome15 |
| Coordinates | This gene maps to 43885251-43891604 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-CKMT1B-11012-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-CKMT1B-11012-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-CKMT1B-11012-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-CKMT1B-11012-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-CKMT1B-11012-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-CKMT1B-11012-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-CKMT1B-11012-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-CKMT1B-11012-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-CKMT1B-11012-REGR | 599nm;515nm | 580nm;491nm |
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