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| Catalog: | GBAFP-CCL5-01163 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (CCL5). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | CCL5 Gene-specific Break Apart Probe is designed to detect potential CCL5 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | C-C Motif Chemokine Ligand 5 |
| Gene Summary [Provided by RefSeq] | This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] |
| Gene Symbol | CCL5 |
| Location | 17q12 |
| Chromosome | Chromosome17 |
| Coordinates | This gene maps to 34198495-34207377 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-CCL5-01163-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-CCL5-01163-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-CCL5-01163-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-CCL5-01163-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-CCL5-01163-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-CCL5-01163-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-CCL5-01163-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-CCL5-01163-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-CCL5-01163-REGR | 599nm;515nm | 580nm;491nm |
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