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| Catalog: | GBAFP-CARD8-00973 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (CARD8). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | CARD8 Gene-specific Break Apart Probe is designed to detect potential CARD8 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Caspase Recruitment Domain Family Member 8 |
| Gene Summary [Provided by RefSeq] | The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010] |
| Gene Symbol | CARD8 |
| Location | 19q13.33 |
| Chromosome | Chromosome19 |
| Coordinates | This gene maps to 48711342-48759203 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-CARD8-00973-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-CARD8-00973-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-CARD8-00973-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-CARD8-00973-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-CARD8-00973-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-CARD8-00973-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-CARD8-00973-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-CARD8-00973-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-CARD8-00973-REGR | 599nm;515nm | 580nm;491nm |
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