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| Catalog: | GBAFP-CAPN10-10574 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (CAPN10). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | CAPN10 Gene-specific Break Apart Probe is designed to detect potential CAPN10 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Calpain 10 |
| Gene Summary [Provided by RefSeq] | Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq, Sep 2010] |
| Gene Symbol | CAPN10 |
| Location | 2q37.3 |
| Chromosome | Chromosome2 |
| Coordinates | This gene maps to 241526132-241538526 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | OR; GR | GBAFP-CAPN10-10574-ORGR | 573nm;515nm | 548nm;491nm | |
| 2 | AQ; OR | GBAFP-CAPN10-10574-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-CAPN10-10574-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-CAPN10-10574-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-CAPN10-10574-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; OR | GBAFP-CAPN10-10574-GROR | 515nm;573nm | 491nm;548nm | |
| 7 | GR; RE | GBAFP-CAPN10-10574-GRRE | 515nm;599nm | 491nm;580nm | |
| 8 | RE; GO | GBAFP-CAPN10-10574-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-CAPN10-10574-REGR | 599nm;515nm | 580nm;491nm |
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