Gene-specific Break Apart Probe-B4GALT1

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Catalog:	GBAFP-B4GALT1-00571
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (B4GALT1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	B4GALT1 Gene-specific Break Apart Probe is designed to detect potential B4GALT1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	Beta-1,4-galactosyltransferase 1
Gene Summary [Provided by RefSeq]	This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose <=> UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5' end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase. [provided by RefSeq, Jul 2008]
Gene Symbol	B4GALT1
Location	9p21.1
Chromosome	Chromosome9
Coordinates	This gene maps to 33110638-33167356 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	GR; OR	GBAFP-B4GALT1-00571-GROR	515nm;573nm	491nm;548nm
2	AQ; OR	GBAFP-B4GALT1-00571-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-B4GALT1-00571-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-B4GALT1-00571-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-B4GALT1-00571-GRGO	515nm;551nm	491nm;525nm
6	GR; RE	GBAFP-B4GALT1-00571-GRRE	515nm;599nm	491nm;580nm
7	OR; GR	GBAFP-B4GALT1-00571-ORGR	573nm;515nm	548nm;491nm
8	RE; GO	GBAFP-B4GALT1-00571-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-B4GALT1-00571-REGR	599nm;515nm	580nm;491nm

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