Gene-specific Break Apart Probe-AVPR2

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Catalog:	GBAFP-AVPR2-10140
Classification:	Gene-specific Break Apart Probes
Description:	Our Gene-specific Break Apart Probes usually target the flanks of the target gene (AVPR2). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent.
Application:	AVPR2 Gene-specific Break Apart Probe is designed to detect potential AVPR2 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services.
Quantity:	20 Tests
Probe Kits Volume (µL):	40 μL
Hybridization Solution (µL):	200 μL
Turnaround Time:	Within 10 Business Days
Shipping Time:	1-2 Day Expedited Shipping
Shipping Conditions:	-20℃
Storage Conditions:	Store at -20℃ and avoid light;

Gene Details

Gene Name	Arginine Vasopressin Receptor 2
Gene Summary [Provided by RefSeq]	This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus (NDI) results. The V2 receptor is also expressed outside the kidney although its tissue localization is uncertain. When these 'extrarenal receptors' are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known - its absence does not appear to be detrimental in NDI patients. The gene expression has also been described in fetal lung tissue and lung cancer associated with alternative splicing. [provided by RefSeq, Jul 2008]
Gene Symbol	AVPR2
Location	Xq28
Chromosome	ChromosomeX
Coordinates	This gene maps to 153167984-153172620 in GRCh37 coordinates.
Species	Human

Order Sheet

Number	Dye Color	Order Name	Absorbance Maximum	Emission Maximum	Add to Cart
1	OR; GR	GBAFP-AVPR2-10140-ORGR	573nm;515nm	548nm;491nm
2	AQ; OR	GBAFP-AVPR2-10140-AQOR	467nm;573nm	418nm;548nm
3	GO; GR	GBAFP-AVPR2-10140-GOGR	551nm;515nm	525nm;491nm
4	GO; RE	GBAFP-AVPR2-10140-GORE	551nm;599nm	525nm;580nm
5	GR; GO	GBAFP-AVPR2-10140-GRGO	515nm;551nm	491nm;525nm
6	GR; OR	GBAFP-AVPR2-10140-GROR	515nm;573nm	491nm;548nm
7	GR; RE	GBAFP-AVPR2-10140-GRRE	515nm;599nm	491nm;580nm
8	RE; GO	GBAFP-AVPR2-10140-REGO	599nm;551nm	580nm;525nm
9	RE; GR	GBAFP-AVPR2-10140-REGR	599nm;515nm	580nm;491nm

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