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| Catalog: | GBAFP-ASCC1-00445 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (ASCC1). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | ASCC1 Gene-specific Break Apart Probe is designed to detect potential ASCC1 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Activating Signal Cointegrator 1 Complex Subunit 1 |
| Gene Summary [Provided by RefSeq] | This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| Gene Symbol | ASCC1 |
| Location | 10q22.1 |
| Chromosome | Chromosome10 |
| Coordinates | This gene maps to 73856273-73976183 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-ASCC1-00445-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-ASCC1-00445-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-ASCC1-00445-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-ASCC1-00445-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-ASCC1-00445-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-ASCC1-00445-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-ASCC1-00445-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-ASCC1-00445-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-ASCC1-00445-REGR | 599nm;515nm | 580nm;491nm |
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