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| Catalog: | GBAFP-ALAD-00185 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (ALAD). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | ALAD Gene-specific Break Apart Probe is designed to detect potential ALAD rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | Aminolevulinate Dehydratase |
| Gene Summary [Provided by RefSeq] | The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] |
| Gene Symbol | ALAD |
| Location | 9q32 |
| Chromosome | Chromosome9 |
| Coordinates | This gene maps to 116148591-116163618 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-ALAD-00185-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-ALAD-00185-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-ALAD-00185-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-ALAD-00185-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-ALAD-00185-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-ALAD-00185-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-ALAD-00185-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-ALAD-00185-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-ALAD-00185-REGR | 599nm;515nm | 580nm;491nm |
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