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| Catalog: | GBAFP-ADAMTS8-00149 |
| Classification: | Gene-specific Break Apart Probes |
| Description: | Our Gene-specific Break Apart Probes usually target the flanks of the target gene (ADAMTS8). Due to this design method, our probe products can detect chromosomal rearrangements, such as translocations, by FISH.The product usually consists of a reagent combination composed of a probe with a selected dye color and a hybridization reagent. |
| Application: | ADAMTS8 Gene-specific Break Apart Probe is designed to detect potential ADAMTS8 rearrangements. This probe has been confirmed on the metaphase and interphase chromosomes by FISH. We provide a variety of dye color combinations for Break Apart Probes for customers to choose from. Probe products not only provide some classic color combinations, but also provide customized probe services. |
| Quantity: | 20 Tests |
| Probe Kits Volume (µL): | 40 μL |
| Hybridization Solution (µL): | 200 μL |
| Turnaround Time: | Within 10 Business Days |
| Shipping Time: | 1-2 Day Expedited Shipping |
| Shipping Conditions: | -20℃ |
| Storage Conditions: | Store at -20℃ and avoid light; |
| Gene Name | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 |
| Gene Summary [Provided by RefSeq] | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. Reduced expression of this gene has been observed in multiple human cancers and this gene has been proposed as a potential tumor suppressor. [provided by RefSeq, Feb 2016] |
| Gene Symbol | ADAMTS8 |
| Location | 11q24.3 |
| Chromosome | Chromosome11 |
| Coordinates | This gene maps to 130274817-130298539 in GRCh37 coordinates. |
| Species | Human |
| Number | Dye Color | Order Name | Absorbance Maximum | Emission Maximum | Add to Cart |
| 1 | GR; OR | GBAFP-ADAMTS8-00149-GROR | 515nm;573nm | 491nm;548nm | |
| 2 | AQ; OR | GBAFP-ADAMTS8-00149-AQOR | 467nm;573nm | 418nm;548nm | |
| 3 | GO; GR | GBAFP-ADAMTS8-00149-GOGR | 551nm;515nm | 525nm;491nm | |
| 4 | GO; RE | GBAFP-ADAMTS8-00149-GORE | 551nm;599nm | 525nm;580nm | |
| 5 | GR; GO | GBAFP-ADAMTS8-00149-GRGO | 515nm;551nm | 491nm;525nm | |
| 6 | GR; RE | GBAFP-ADAMTS8-00149-GRRE | 515nm;599nm | 491nm;580nm | |
| 7 | OR; GR | GBAFP-ADAMTS8-00149-ORGR | 573nm;515nm | 548nm;491nm | |
| 8 | RE; GO | GBAFP-ADAMTS8-00149-REGO | 599nm;551nm | 580nm;525nm | |
| 9 | RE; GR | GBAFP-ADAMTS8-00149-REGR | 599nm;515nm | 580nm;491nm |
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