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ZNF331-NLRP4 Gene Fusion FISH Probe

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Catalog: GFFP-ZNF331/NLRP4-13614
Classification: Gene Fusion FISH Probes
Description: The ZNF331-NLRP4 Gene Fusion FISH Probecan detect the fusion of ZNF331 and NLRP4 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: ZNF331-NLRP4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Zinc Finger Protein 331
Gene Summary 1 This gene encodes a zinc finger protein containing a KRAB (Kruppel-associated box) domain found in transcriptional repressors. This gene may be methylated and silenced in cancer cells. This gene is located within a differentially methylated region (DMR) and shows allele-specific expression in placenta. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding the same protein. [provided by RefSeq, Nov 2015]
Chromosome 1 Chromosome 19
Locus 1 19q13.42
Coordinates 1 This gene maps to 54024176-54083523 in GRCh37 coordinates.
Gene Name 2 NLR Family Pyrin Domain Containing 4
Gene Summary 2 The protein encoded by this gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). This gene product has a demonstrated role as a negative regulator of autophagy and type I interferon signaling pathways as a result of protein interactions with its NACHT domain. The PYD domain has also been shown to be important in the inhibition of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells). [provided by RefSeq, Dec 2016]
Chromosome 2 Chromosome19
Locus 2 19q13.43
Coordinates 2 This gene maps to 56347943-56393220 in GRCh37 coordinates.
Associated Diseases Lung Squamous Cell Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-ZNF331/NLRP4-13614-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-ZNF331/NLRP4-13614-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-ZNF331/NLRP4-13614-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-ZNF331/NLRP4-13614-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-ZNF331/NLRP4-13614-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-ZNF331/NLRP4-13614-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-ZNF331/NLRP4-13614-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-ZNF331/NLRP4-13614-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-ZNF331/NLRP4-13614-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-ZNF331/NLRP4-13614-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-ZNF331/NLRP4-13614-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-ZNF331/NLRP4-13614-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-ZNF331/NLRP4-13614-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-ZNF331/NLRP4-13614-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-ZNF331/NLRP4-13614-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-ZNF331/NLRP4-13614-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-ZNF331/NLRP4-13614-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-ZNF331/NLRP4-13614-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-ZNF331/NLRP4-13614-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-ZNF331/NLRP4-13614-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-ZNF331/NLRP4-13614-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-ZNF331/NLRP4-13614-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-ZNF331/NLRP4-13614-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-ZNF331/NLRP4-13614-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-ZNF331/NLRP4-13614-AQAQ 467nm;467nm 418nm;418nm

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