ZNF292-GRM4 Gene Fusion FISH Probe
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Catalog: |
GFFP-ZNF292/GRM4-15780 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The ZNF292-GRM4 Gene Fusion FISH Probe can detect the fusion of ABCA5 and BCAS3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
ZNF292-GRM4 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Glutamate Metabotropic Receptor 4 |
Gene Summary 1 |
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] |
Chromosome 1 |
Chromosome 6 |
Locus 1 |
6p21.31 |
Coordinates 1 |
This gene maps to 33989627-34101443in GRCh37 coordinates. |
Gene Name 2 |
Zinc Finger Protein 292 |
Gene Summary 2 |
This gene encodes a growth hormone-dependent, zinc finger transcription factor that functions as a tumor suppressor. Naturally occurring mutations in this gene are associated with gastric cancer, colorectal cancer, and chronic lymphocytic leukemia. [provided by RefSeq, May 2017] |
Chromosome 2 |
Chromosome6 |
Locus 2 |
6q14.3 |
Coordinates 2 |
This gene maps to 87865268-87973406 in GRCh37 coordinates. |
Associated Diseases |
Brain Lower Grade Glioma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-ZNF292/GRM4-15780-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-ZNF292/GRM4-15780-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-ZNF292/GRM4-15780-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-ZNF292/GRM4-15780-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-ZNF292/GRM4-15780-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-ZNF292/GRM4-15780-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-ZNF292/GRM4-15780-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-ZNF292/GRM4-15780-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-ZNF292/GRM4-15780-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-ZNF292/GRM4-15780-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-ZNF292/GRM4-15780-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-ZNF292/GRM4-15780-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-ZNF292/GRM4-15780-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-ZNF292/GRM4-15780-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-ZNF292/GRM4-15780-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-ZNF292/GRM4-15780-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-ZNF292/GRM4-15780-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-ZNF292/GRM4-15780-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-ZNF292/GRM4-15780-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-ZNF292/GRM4-15780-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-ZNF292/GRM4-15780-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-ZNF292/GRM4-15780-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-ZNF292/GRM4-15780-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-ZNF292/GRM4-15780-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-ZNF292/GRM4-15780-AQAQ |
467nm;467nm |
418nm;418nm |
|
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