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ZCCHC8-TOP3A Gene Fusion FISH Probe

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Catalog: GFFP-ZCCHC8/TOP3A-13454
Classification: Gene Fusion FISH Probes
Description: The ZCCHC8-TOP3A Gene Fusion FISH Probecan detect the fusion of ZCCHC8 and TOP3A genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: ZCCHC8-TOP3A Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 DNA Topoisomerase III Alpha
Gene Summary 1 This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Chromosome 1 Chromosome 17
Locus 1 17p11.2
Coordinates 1 This gene maps to 18177234-18218321 in GRCh37 coordinates.
Gene Name 2 Zinc Finger CCHC-type Containing 8
Gene Summary 2 This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain. [provided by RefSeq, Apr 2017]
Chromosome 2 Chromosome12
Locus 2 12q24.31
Coordinates 2 This gene maps to 122956145-122985543 in GRCh37 coordinates.
Associated Diseases Bladder Urothelial Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-ZCCHC8/TOP3A-13454-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-ZCCHC8/TOP3A-13454-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-ZCCHC8/TOP3A-13454-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-ZCCHC8/TOP3A-13454-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-ZCCHC8/TOP3A-13454-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-ZCCHC8/TOP3A-13454-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-ZCCHC8/TOP3A-13454-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-ZCCHC8/TOP3A-13454-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-ZCCHC8/TOP3A-13454-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-ZCCHC8/TOP3A-13454-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-ZCCHC8/TOP3A-13454-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-ZCCHC8/TOP3A-13454-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-ZCCHC8/TOP3A-13454-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-ZCCHC8/TOP3A-13454-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-ZCCHC8/TOP3A-13454-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-ZCCHC8/TOP3A-13454-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-ZCCHC8/TOP3A-13454-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-ZCCHC8/TOP3A-13454-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-ZCCHC8/TOP3A-13454-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-ZCCHC8/TOP3A-13454-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-ZCCHC8/TOP3A-13454-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-ZCCHC8/TOP3A-13454-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-ZCCHC8/TOP3A-13454-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-ZCCHC8/TOP3A-13454-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-ZCCHC8/TOP3A-13454-AQAQ 467nm;467nm 418nm;418nm

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