XPO6-FBXO31 Gene Fusion FISH Probe
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Catalog: |
GFFP-XPO6/FBXO31-13234 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The XPO6-FBXO31 Gene Fusion FISH Probecan detect the fusion of XPO6 and FBXO31 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
XPO6-FBXO31 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Exportin 6 |
Gene Summary 1 |
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012] |
Chromosome 1 |
Chromosome 16 |
Locus 1 |
16p12.1 |
Coordinates 1 |
This gene maps to 28109315-28223190 in GRCh37 coordinates. |
Gene Name 2 |
F-box Protein 31 |
Gene Summary 2 |
This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
Chromosome 2 |
Chromosome16 |
Locus 2 |
16q24.2 |
Coordinates 2 |
This gene maps to 87362941-87425708 in GRCh37 coordinates. |
Associated Diseases |
Bladder Urothelial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
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1 |
RE; RE
|
GFFP-XPO6/FBXO31-13234-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-XPO6/FBXO31-13234-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-XPO6/FBXO31-13234-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-XPO6/FBXO31-13234-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-XPO6/FBXO31-13234-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-XPO6/FBXO31-13234-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-XPO6/FBXO31-13234-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-XPO6/FBXO31-13234-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-XPO6/FBXO31-13234-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-XPO6/FBXO31-13234-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-XPO6/FBXO31-13234-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-XPO6/FBXO31-13234-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-XPO6/FBXO31-13234-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-XPO6/FBXO31-13234-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-XPO6/FBXO31-13234-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-XPO6/FBXO31-13234-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-XPO6/FBXO31-13234-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-XPO6/FBXO31-13234-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-XPO6/FBXO31-13234-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-XPO6/FBXO31-13234-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-XPO6/FBXO31-13234-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-XPO6/FBXO31-13234-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-XPO6/FBXO31-13234-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-XPO6/FBXO31-13234-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-XPO6/FBXO31-13234-AQAQ |
467nm;467nm |
418nm;418nm |
|
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