WNT7B-LRP6 Gene Fusion FISH Probe
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Catalog: |
GFFP-WNT7B/LRP6-13275 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The WNT7B-LRP6 Gene Fusion FISH Probecan detect the fusion of WNT7B and LRP6 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
WNT7B-LRP6 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
LDL Receptor Related Protein 6 |
Gene Summary 1 |
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009] |
Chromosome 1 |
Chromosome 12 |
Locus 1 |
12p13.2 |
Coordinates 1 |
This gene maps to 12268960-12419811 in GRCh37 coordinates. |
Gene Name 2 |
Wnt Family Member 7B |
Gene Summary 2 |
This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Among members of the human WNT family, this gene product is most similar to WNT7A protein. [provided by RefSeq, Oct 2008] |
Chromosome 2 |
Chromosome22 |
Locus 2 |
22q13.31 |
Coordinates 2 |
This gene maps to 46316247-46373008 in GRCh37 coordinates. |
Associated Diseases |
Breast Invasive Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-WNT7B/LRP6-13275-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-WNT7B/LRP6-13275-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-WNT7B/LRP6-13275-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-WNT7B/LRP6-13275-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-WNT7B/LRP6-13275-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-WNT7B/LRP6-13275-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-WNT7B/LRP6-13275-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-WNT7B/LRP6-13275-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-WNT7B/LRP6-13275-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-WNT7B/LRP6-13275-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-WNT7B/LRP6-13275-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-WNT7B/LRP6-13275-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-WNT7B/LRP6-13275-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-WNT7B/LRP6-13275-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-WNT7B/LRP6-13275-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-WNT7B/LRP6-13275-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-WNT7B/LRP6-13275-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-WNT7B/LRP6-13275-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-WNT7B/LRP6-13275-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-WNT7B/LRP6-13275-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-WNT7B/LRP6-13275-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-WNT7B/LRP6-13275-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-WNT7B/LRP6-13275-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-WNT7B/LRP6-13275-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-WNT7B/LRP6-13275-AQAQ |
467nm;467nm |
418nm;418nm |
|
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