WNK3-FGD1 Gene Fusion FISH Probe
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Catalog: |
GFFP-WNK3/FGD1-13276 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The WNK3-FGD1 Gene Fusion FISH Probecan detect the fusion of WNK3 and FGD1 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
WNK3-FGD1 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
FYVE, RhoGEF And PH Domain Containing 1 |
Gene Summary 1 |
This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of the faciogenital dysplasia in Aarskog-Scott syndrome and a syndromatic form of X-linked cognitive disability. [provided by RefSeq, Jul 2017] |
Chromosome 1 |
Chromosome X |
Locus 1 |
Xp11.22 |
Coordinates 1 |
This gene maps to 54471886-54522599 in GRCh37 coordinates. |
Gene Name 2 |
WNK Lysine Deficient Protein Kinase 3 |
Gene Summary 2 |
This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
Chromosome 2 |
ChromosomeX |
Locus 2 |
Xp11.22 |
Coordinates 2 |
This gene maps to 54219255-54384438 in GRCh37 coordinates. |
Associated Diseases |
Uterine Corpus Endometrial Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-WNK3/FGD1-13276-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-WNK3/FGD1-13276-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-WNK3/FGD1-13276-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-WNK3/FGD1-13276-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-WNK3/FGD1-13276-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-WNK3/FGD1-13276-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-WNK3/FGD1-13276-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-WNK3/FGD1-13276-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-WNK3/FGD1-13276-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-WNK3/FGD1-13276-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-WNK3/FGD1-13276-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-WNK3/FGD1-13276-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-WNK3/FGD1-13276-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-WNK3/FGD1-13276-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-WNK3/FGD1-13276-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-WNK3/FGD1-13276-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-WNK3/FGD1-13276-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-WNK3/FGD1-13276-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-WNK3/FGD1-13276-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-WNK3/FGD1-13276-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-WNK3/FGD1-13276-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-WNK3/FGD1-13276-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-WNK3/FGD1-13276-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-WNK3/FGD1-13276-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-WNK3/FGD1-13276-AQAQ |
467nm;467nm |
418nm;418nm |
|
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