WDR18-H2AFX Gene Fusion FISH Probe
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Catalog: |
GFFP-WDR18/H2AFX-13051 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The WDR18-H2AFX Gene Fusion FISH Probecan detect the fusion of WDR18 and H2AFX genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
WDR18-H2AFX Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
H2A Histone Family Member X |
Gene Summary 1 |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015] |
Chromosome 1 |
Chromosome 11 |
Locus 1 |
11q23.3 |
Coordinates 1 |
This gene maps to 118964584-118966177 in GRCh37 coordinates. |
Gene Name 2 |
WD Repeat Domain 18 |
Gene Summary 2 |
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome19 |
Locus 2 |
19p13.3 |
Coordinates 2 |
This gene maps to 984327-994569 in GRCh37 coordinates. |
Associated Diseases |
Acute Myeloid Leukemia |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-WDR18/H2AFX-13051-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-WDR18/H2AFX-13051-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-WDR18/H2AFX-13051-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-WDR18/H2AFX-13051-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-WDR18/H2AFX-13051-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-WDR18/H2AFX-13051-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-WDR18/H2AFX-13051-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-WDR18/H2AFX-13051-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-WDR18/H2AFX-13051-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-WDR18/H2AFX-13051-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-WDR18/H2AFX-13051-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-WDR18/H2AFX-13051-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-WDR18/H2AFX-13051-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-WDR18/H2AFX-13051-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-WDR18/H2AFX-13051-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-WDR18/H2AFX-13051-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-WDR18/H2AFX-13051-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-WDR18/H2AFX-13051-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-WDR18/H2AFX-13051-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-WDR18/H2AFX-13051-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-WDR18/H2AFX-13051-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-WDR18/H2AFX-13051-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-WDR18/H2AFX-13051-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-WDR18/H2AFX-13051-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-WDR18/H2AFX-13051-AQAQ |
467nm;467nm |
418nm;418nm |
|
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