VPS72-ROBO2 Gene Fusion FISH Probe
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Catalog: |
GFFP-VPS72/ROBO2-13111 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The VPS72-ROBO2 Gene Fusion FISH Probecan detect the fusion of VPS72 and ROBO2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
VPS72-ROBO2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Roundabout Guidance Receptor 2 |
Gene Summary 1 |
The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
Chromosome 1 |
Chromosome 3 |
Locus 1 |
3p12.3 |
Coordinates 1 |
This gene maps to 77089293-77699114 in GRCh37 coordinates. |
Gene Name 2 |
Vacuolar Protein Sorting 72 Homolog |
Gene Summary 2 |
The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012] |
Chromosome 2 |
Chromosome1 |
Locus 2 |
1q21.3 |
Coordinates 2 |
This gene maps to 151148933-151162640 in GRCh37 coordinates. |
Associated Diseases |
Lung Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-VPS72/ROBO2-13111-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-VPS72/ROBO2-13111-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-VPS72/ROBO2-13111-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-VPS72/ROBO2-13111-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-VPS72/ROBO2-13111-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-VPS72/ROBO2-13111-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-VPS72/ROBO2-13111-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-VPS72/ROBO2-13111-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-VPS72/ROBO2-13111-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-VPS72/ROBO2-13111-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-VPS72/ROBO2-13111-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-VPS72/ROBO2-13111-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-VPS72/ROBO2-13111-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-VPS72/ROBO2-13111-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-VPS72/ROBO2-13111-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-VPS72/ROBO2-13111-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-VPS72/ROBO2-13111-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-VPS72/ROBO2-13111-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-VPS72/ROBO2-13111-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-VPS72/ROBO2-13111-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-VPS72/ROBO2-13111-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-VPS72/ROBO2-13111-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-VPS72/ROBO2-13111-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-VPS72/ROBO2-13111-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-VPS72/ROBO2-13111-AQAQ |
467nm;467nm |
418nm;418nm |
|
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