VPS18-NTRK3 Gene Fusion FISH Probe
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Catalog: |
GFFP-VPS18/NTRK3-13135 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The VPS18-NTRK3 Gene Fusion FISH Probecan detect the fusion of VPS18 and NTRK3 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
VPS18-NTRK3 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Neurotrophic Receptor Tyrosine Kinase 3 |
Gene Summary 1 |
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] |
Chromosome 1 |
Chromosome 15 |
Locus 1 |
15q25.3 |
Coordinates 1 |
This gene maps to 88419987-88799962 in GRCh37 coordinates. |
Gene Name 2 |
VPS18, CORVET/HOPS Core Subunit |
Gene Summary 2 |
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome15 |
Locus 2 |
15q15.1 |
Coordinates 2 |
This gene maps to 41186627-41196173 in GRCh37 coordinates. |
Associated Diseases |
Colon Adenocarcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-VPS18/NTRK3-13135-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-VPS18/NTRK3-13135-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-VPS18/NTRK3-13135-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-VPS18/NTRK3-13135-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-VPS18/NTRK3-13135-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-VPS18/NTRK3-13135-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-VPS18/NTRK3-13135-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-VPS18/NTRK3-13135-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-VPS18/NTRK3-13135-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-VPS18/NTRK3-13135-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-VPS18/NTRK3-13135-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-VPS18/NTRK3-13135-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-VPS18/NTRK3-13135-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-VPS18/NTRK3-13135-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-VPS18/NTRK3-13135-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-VPS18/NTRK3-13135-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-VPS18/NTRK3-13135-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-VPS18/NTRK3-13135-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-VPS18/NTRK3-13135-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-VPS18/NTRK3-13135-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-VPS18/NTRK3-13135-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-VPS18/NTRK3-13135-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-VPS18/NTRK3-13135-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-VPS18/NTRK3-13135-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-VPS18/NTRK3-13135-AQAQ |
467nm;467nm |
418nm;418nm |
|
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