VHL-KIAA1430 Gene Fusion FISH Probe
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Catalog: |
GFFP-VHL/KIAA1430-13153 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The VHL-KIAA1430 Gene Fusion FISH Probecan detect the fusion of VHL and KIAA1430 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
VHL-KIAA1430 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Von Hippel-Lindau Tumor Suppressor |
Gene Summary 1 |
Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 3 |
Locus 1 |
3p25.3 |
Coordinates 1 |
This gene maps to 10183318-10195354 in GRCh37 coordinates. |
Associated Diseases |
Kidney Renal Clear Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-VHL/KIAA1430-13153-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-VHL/KIAA1430-13153-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-VHL/KIAA1430-13153-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-VHL/KIAA1430-13153-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-VHL/KIAA1430-13153-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-VHL/KIAA1430-13153-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-VHL/KIAA1430-13153-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-VHL/KIAA1430-13153-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-VHL/KIAA1430-13153-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-VHL/KIAA1430-13153-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-VHL/KIAA1430-13153-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-VHL/KIAA1430-13153-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-VHL/KIAA1430-13153-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-VHL/KIAA1430-13153-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-VHL/KIAA1430-13153-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-VHL/KIAA1430-13153-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-VHL/KIAA1430-13153-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-VHL/KIAA1430-13153-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-VHL/KIAA1430-13153-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-VHL/KIAA1430-13153-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-VHL/KIAA1430-13153-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-VHL/KIAA1430-13153-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-VHL/KIAA1430-13153-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-VHL/KIAA1430-13153-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-VHL/KIAA1430-13153-AQAQ |
467nm;467nm |
418nm;418nm |
|
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