VCL-SEC24C Gene Fusion FISH Probe
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Catalog: |
GFFP-VCL/SEC24C-14734 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The VCL-SEC24C Gene Fusion FISH Probecan detect the fusion of VCL and SEC24C genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
VCL-SEC24C Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Vinculin |
Gene Summary 1 |
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] |
Chromosome 1 |
Chromosome 10 |
Locus 1 |
10q22.2 |
Coordinates 1 |
This gene maps to 75757871-75879914 in GRCh37 coordinates. |
Gene Name 2 |
SEC24 Homolog C, COPII Coat Complex Component |
Gene Summary 2 |
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
Chromosome 2 |
Chromosome10 |
Locus 2 |
10q22.2 |
Coordinates 2 |
This gene maps to 75504130-75531933 in GRCh37 coordinates. |
Associated Diseases |
Head And Neck Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-VCL/SEC24C-14734-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-VCL/SEC24C-14734-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-VCL/SEC24C-14734-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-VCL/SEC24C-14734-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-VCL/SEC24C-14734-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-VCL/SEC24C-14734-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-VCL/SEC24C-14734-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-VCL/SEC24C-14734-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-VCL/SEC24C-14734-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-VCL/SEC24C-14734-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-VCL/SEC24C-14734-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-VCL/SEC24C-14734-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-VCL/SEC24C-14734-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-VCL/SEC24C-14734-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-VCL/SEC24C-14734-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-VCL/SEC24C-14734-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-VCL/SEC24C-14734-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-VCL/SEC24C-14734-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-VCL/SEC24C-14734-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-VCL/SEC24C-14734-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-VCL/SEC24C-14734-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-VCL/SEC24C-14734-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-VCL/SEC24C-14734-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-VCL/SEC24C-14734-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-VCL/SEC24C-14734-AQAQ |
467nm;467nm |
418nm;418nm |
|
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