banner
  • Home
  • USP48-HSPG2 Gene Fusion FISH Probe

USP48-HSPG2 Gene Fusion FISH Probe

Add to Cart
Catalog: GFFP-USP48/HSPG2-12974
Classification: Gene Fusion FISH Probes
Description: The USP48-HSPG2 Gene Fusion FISH Probecan detect the fusion of USP48 and HSPG2 genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality.
Category: Gene Fusion FISH Probes
Application: USP48-HSPG2 Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads ​of normal peripheral blood. This is key quality control, you can trust our quality.
Probe Kits Volume (µL): 40 μL
Quantity: 20 Tests
Hybridization Solution (µL): 200 μL
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping
Storage Conditions: Store at -20℃ and avoid light;
Shipping Conditions: -20℃

Gene Details

Gene Name 1 Heparan Sulfate Proteoglycan 2
Gene Summary 1 This gene encodes the perlecan protein, which consists of a core protein to which three long chains of glycosaminoglycans (heparan sulfate or chondroitin sulfate) are attached. The perlecan protein is a large multidomain proteoglycan that binds to and cross-links many extracellular matrix components and cell-surface molecules. It has been shown that this protein interacts with laminin, prolargin, collagen type IV, FGFBP1, FBLN2, FGF7 and transthyretin, etc., and it plays essential roles in multiple biological activities. Perlecan is a key component of the vascular extracellular matrix, where it helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. It can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation. It is a major component of basement membranes, where it is involved in the stabilization of other molecules as well as being involved with glomerular permeability to macromolecules and cell adhesion. Mutations in this gene cause Schwartz-Jampel syndrome type 1, Silverman-Handmaker type of dyssegmental dysplasia, and tardive dyskinesia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
Chromosome 1 Chromosome 1
Locus 1 1p36.12
Coordinates 1 This gene maps to 22148736-22263750 in GRCh37 coordinates.
Gene Name 2 Ubiquitin Specific Peptidase 48
Gene Summary 2 This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Chromosome 2 Chromosome1
Locus 2 1p36.12
Coordinates 2 This gene maps to 22004791-22109688 in GRCh37 coordinates.
Associated Diseases Uterine Corpus Endometrial Carcinoma
Species Human

Order Sheet

Number Dye Color Order Name Absorbance Maximum Emission Maximum Add to Cart
1 RE; RE GFFP-USP48/HSPG2-12974-RERE 599nm;599nm 580nm;580nm
2 RE; OR GFFP-USP48/HSPG2-12974-REOR 599nm;573nm 580nm;548nm
3 RE; GO GFFP-USP48/HSPG2-12974-REGO 599nm;551nm 580nm;525nm
4 RE; GR GFFP-USP48/HSPG2-12974-REGR 599nm;515nm 580nm;491nm
5 RE; AQ GFFP-USP48/HSPG2-12974-REAQ 599nm;467nm 580nm;418nm
6 OR; RE GFFP-USP48/HSPG2-12974-ORRE 573nm;599nm 548nm;580nm
7 OR; OR GFFP-USP48/HSPG2-12974-OROR 573nm;573nm 548nm;548nm
8 OR; GO GFFP-USP48/HSPG2-12974-ORGO 573nm;551nm 548nm;525nm
9 OR; GR GFFP-USP48/HSPG2-12974-ORGR 573nm;515nm 548nm;491nm
10 OR; AQ GFFP-USP48/HSPG2-12974-ORAQ 573nm;467nm 548nm;418nm
11 GO; RE GFFP-USP48/HSPG2-12974-GORE 551nm;599nm 525nm;580nm
12 GO; OR GFFP-USP48/HSPG2-12974-GOOR 551nm;573nm 525nm;548nm
13 GO; GO GFFP-USP48/HSPG2-12974-GOGO 551nm;551nm 525nm;525nm
14 GO; GR GFFP-USP48/HSPG2-12974-GOGR 551nm;515nm 525nm;491nm
15 GO; AQ GFFP-USP48/HSPG2-12974-GOAQ 551nm;467nm 525nm;418nm
16 GR; RE GFFP-USP48/HSPG2-12974-GRRE 515nm;599nm 491nm;580nm
17 GR; OR GFFP-USP48/HSPG2-12974-GROR 515nm;573nm 491nm;548nm
18 GR; GO GFFP-USP48/HSPG2-12974-GRGO 515nm;551nm 491nm;525nm
19 GR; GR GFFP-USP48/HSPG2-12974-GRGR 515nm;515nm 491nm;491nm
20 GR; AQ GFFP-USP48/HSPG2-12974-GRAQ 515nm;467nm 491nm;418nm
21 AQ; RE GFFP-USP48/HSPG2-12974-AQRE 467nm;599nm 418nm;580nm
22 AQ; OR GFFP-USP48/HSPG2-12974-AQOR 467nm;573nm 418nm;548nm
23 AQ; GO GFFP-USP48/HSPG2-12974-AQGO 467nm;551nm 418nm;525nm
24 AQ; GR GFFP-USP48/HSPG2-12974-AQGR 467nm;515nm 418nm;491nm
25 AQ; AQ GFFP-USP48/HSPG2-12974-AQAQ 467nm;467nm 418nm;418nm

Other Products

Online Inquiry

Order

0
Inquiry Basket ( 0 ) Choose Dye*