USP25-PCNT Gene Fusion FISH Probe
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Catalog: |
GFFP-USP25/PCNT-14720 |
Classification: |
Gene Fusion FISH Probes |
Description: |
The USP25-PCNT Gene Fusion FISH Probecan detect the fusion of USP25 and PCNT genes. Our product usually consists of a combination of reagents, which consists of a probe with a selected dye color and a hybridization reagent. We offer a variety of dye color combinations for FISH probes for gene fusions. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Category: |
Gene Fusion FISH Probes |
Application: |
USP25-PCNT Gene Fusion FISH Probe can be used for chromosomal diagnosis to determine gene fusion phenomena associated with diseases such as cancer. You can confirm this in "Associated Diseases" in the product information. This product has been verified in both interphase nuclei and metaphase spreads of normal peripheral blood. This is key quality control, you can trust our quality. |
Probe Kits Volume (µL): |
40 μL |
Quantity: |
20 Tests |
Hybridization Solution (µL): |
200 μL |
Turnaround Time: |
7-10 Business Days |
Shipping Time: |
1-2 Day Expedited Shipping |
Storage Conditions: |
Store at -20℃ and avoid light; |
Shipping Conditions: |
-20℃ |
Gene Details
Gene Name 1 |
Pericentrin |
Gene Summary 1 |
The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] |
Chromosome 1 |
Chromosome 21 |
Locus 1 |
21q22.3 |
Coordinates 1 |
This gene maps to 47744035-47865682 in GRCh37 coordinates. |
Gene Name 2 |
Ubiquitin Specific Peptidase 25 |
Gene Summary 2 |
Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 [PubMed 10644437]).[supplied by OMIM, Mar 2008] |
Chromosome 2 |
Chromosome21 |
Locus 2 |
21q21.1 |
Coordinates 2 |
This gene maps to 17102495-17252377 in GRCh37 coordinates. |
Associated Diseases |
Head And Neck Squamous Cell Carcinoma |
Species |
Human |
Dye Colors:
RE
RE
RE
OR
RE
GO
RE
GR
RE
AQ
OR
RE
OR
OR
OR
GO
OR
GR
OR
AQ
GO
RE
GO
OR
GO
GO
GO
GR
GO
AQ
GR
RE
GR
OR
GR
GO
GR
GR
GR
AQ
AQ
RE
AQ
OR
AQ
GO
AQ
GR
AQ
AQ
Order Sheet
Number |
Dye Color |
Order Name |
Absorbance Maximum |
Emission Maximum |
Add to Cart |
1 |
RE; RE
|
GFFP-USP25/PCNT-14720-RERE |
599nm;599nm |
580nm;580nm |
|
2 |
RE; OR
|
GFFP-USP25/PCNT-14720-REOR |
599nm;573nm |
580nm;548nm |
|
3 |
RE; GO
|
GFFP-USP25/PCNT-14720-REGO |
599nm;551nm |
580nm;525nm |
|
4 |
RE; GR
|
GFFP-USP25/PCNT-14720-REGR |
599nm;515nm |
580nm;491nm |
|
5 |
RE; AQ
|
GFFP-USP25/PCNT-14720-REAQ |
599nm;467nm |
580nm;418nm |
|
6 |
OR; RE
|
GFFP-USP25/PCNT-14720-ORRE |
573nm;599nm |
548nm;580nm |
|
7 |
OR; OR
|
GFFP-USP25/PCNT-14720-OROR |
573nm;573nm |
548nm;548nm |
|
8 |
OR; GO
|
GFFP-USP25/PCNT-14720-ORGO |
573nm;551nm |
548nm;525nm |
|
9 |
OR; GR
|
GFFP-USP25/PCNT-14720-ORGR |
573nm;515nm |
548nm;491nm |
|
10 |
OR; AQ
|
GFFP-USP25/PCNT-14720-ORAQ |
573nm;467nm |
548nm;418nm |
|
11 |
GO; RE
|
GFFP-USP25/PCNT-14720-GORE |
551nm;599nm |
525nm;580nm |
|
12 |
GO; OR
|
GFFP-USP25/PCNT-14720-GOOR |
551nm;573nm |
525nm;548nm |
|
13 |
GO; GO
|
GFFP-USP25/PCNT-14720-GOGO |
551nm;551nm |
525nm;525nm |
|
14 |
GO; GR
|
GFFP-USP25/PCNT-14720-GOGR |
551nm;515nm |
525nm;491nm |
|
15 |
GO; AQ
|
GFFP-USP25/PCNT-14720-GOAQ |
551nm;467nm |
525nm;418nm |
|
16 |
GR; RE
|
GFFP-USP25/PCNT-14720-GRRE |
515nm;599nm |
491nm;580nm |
|
17 |
GR; OR
|
GFFP-USP25/PCNT-14720-GROR |
515nm;573nm |
491nm;548nm |
|
18 |
GR; GO
|
GFFP-USP25/PCNT-14720-GRGO |
515nm;551nm |
491nm;525nm |
|
19 |
GR; GR
|
GFFP-USP25/PCNT-14720-GRGR |
515nm;515nm |
491nm;491nm |
|
20 |
GR; AQ
|
GFFP-USP25/PCNT-14720-GRAQ |
515nm;467nm |
491nm;418nm |
|
21 |
AQ; RE
|
GFFP-USP25/PCNT-14720-AQRE |
467nm;599nm |
418nm;580nm |
|
22 |
AQ; OR
|
GFFP-USP25/PCNT-14720-AQOR |
467nm;573nm |
418nm;548nm |
|
23 |
AQ; GO
|
GFFP-USP25/PCNT-14720-AQGO |
467nm;551nm |
418nm;525nm |
|
24 |
AQ; GR
|
GFFP-USP25/PCNT-14720-AQGR |
467nm;515nm |
418nm;491nm |
|
25 |
AQ; AQ
|
GFFP-USP25/PCNT-14720-AQAQ |
467nm;467nm |
418nm;418nm |
|
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